Bills return home to host division rival Patriots: What Underdog odds & data models say for Week 4

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Buffalo Bills quarterback Josh Allen during an NFL football game against the New England Patriots at Gillette Stadium, Sunday, Dec. 14, 2025 in Foxborough, Mass.

The Buffalo Bills (3-0) return to Highmark Stadium on Sunday, October 4 (1:00 PM ET, CBS) for an AFC East matchup with the New England Patriots (1-2). Unlike last week, Joe Brady’s receiver room is in good shape. D.J. Moore (AC joint) and Keon Coleman (ankle) both practiced on a limited basis all week, and neither carries a game designation. Brady said Coleman will “be ready to rock.” Buffalo’s injury concerns are now on defense. Top cornerback Christian Benford (toe) is questionable after missing every practice, and defensive lineman T.J. Sanders (illness) is doubtful.



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